diff --git a/pkg/cmd/gist/clone/clone.go b/pkg/cmd/gist/clone/clone.go
index c1dfee31b..41fa104fa 100644
--- a/pkg/cmd/gist/clone/clone.go
+++ b/pkg/cmd/gist/clone/clone.go
@@ -7,6 +7,7 @@ import (
 	"github.com/MakeNowJust/heredoc"
 	"github.com/cli/cli/v2/git"
 	"github.com/cli/cli/v2/internal/config"
+	"github.com/cli/cli/v2/internal/ghinstance"
 	"github.com/cli/cli/v2/pkg/cmdutil"
 	"github.com/cli/cli/v2/pkg/iostreams"
 	"github.com/spf13/cobra"
@@ -92,9 +93,15 @@ func cloneRun(opts *CloneOptions) error {
 }
 
 func formatRemoteURL(hostname string, gistID string, protocol string) string {
+	if ghinstance.IsEnterprise(hostname) {
+		if protocol == "ssh" {
+			return fmt.Sprintf("git@%s:gist/%s.git", hostname, gistID)
+		}
+		return fmt.Sprintf("https://%s/gist/%s.git", hostname, gistID)
+	}
+
 	if protocol == "ssh" {
 		return fmt.Sprintf("git@gist.%s:%s.git", hostname, gistID)
 	}
-
 	return fmt.Sprintf("https://gist.%s/%s.git", hostname, gistID)
 }
diff --git a/pkg/cmd/gist/clone/clone_test.go b/pkg/cmd/gist/clone/clone_test.go
index ebf9b5c31..ccca76b25 100644
--- a/pkg/cmd/gist/clone/clone_test.go
+++ b/pkg/cmd/gist/clone/clone_test.go
@@ -116,3 +116,60 @@ func Test_GistClone_flagError(t *testing.T) {
 		t.Errorf("unexpected error %v", err)
 	}
 }
+
+func Test_formatRemoteURL(t *testing.T) {
+	type args struct {
+		hostname string
+		gistID   string
+		protocol string
+	}
+	tests := []struct {
+		name string
+		args args
+		want string
+	}{
+		{
+			name: "github.com HTTPS",
+			args: args{
+				hostname: "github.com",
+				protocol: "https",
+				gistID:   "ID",
+			},
+			want: "https://gist.github.com/ID.git",
+		},
+		{
+			name: "github.com SSH",
+			args: args{
+				hostname: "github.com",
+				protocol: "ssh",
+				gistID:   "ID",
+			},
+			want: "git@gist.github.com:ID.git",
+		},
+		{
+			name: "Enterprise HTTPS",
+			args: args{
+				hostname: "acme.org",
+				protocol: "https",
+				gistID:   "ID",
+			},
+			want: "https://acme.org/gist/ID.git",
+		},
+		{
+			name: "Enterprise SSH",
+			args: args{
+				hostname: "acme.org",
+				protocol: "ssh",
+				gistID:   "ID",
+			},
+			want: "git@acme.org:gist/ID.git",
+		},
+	}
+	for _, tt := range tests {
+		t.Run(tt.name, func(t *testing.T) {
+			if got := formatRemoteURL(tt.args.hostname, tt.args.gistID, tt.args.protocol); got != tt.want {
+				t.Errorf("formatRemoteURL() = %v, want %v", got, tt.want)
+			}
+		})
+	}
+}