diff --git a/api/queries_pr.go b/api/queries_pr.go
index c0b16f3c4..b3d380240 100644
--- a/api/queries_pr.go
+++ b/api/queries_pr.go
@@ -953,6 +953,27 @@ func PullRequestMerge(client *Client, repo ghrepo.Interface, pr *PullRequest, m
 	return err
 }
 
+func PullRequestReady(client *Client, repo ghrepo.Interface, pr *PullRequest) error {
+	var mutation struct {
+		MarkPullRequestReadyForReviewInput struct {
+			PullRequest struct {
+				ID githubv4.ID
+			}
+		} `graphql:"markPullRequestReadyForReview(input: $input)"`
+	}
+
+	type MarkPullRequestReadyForReviewInput struct {
+		PullRequestID githubv4.ID `json:"pullRequestId"`
+	}
+
+	input := MarkPullRequestReadyForReviewInput{PullRequestID: pr.ID}
+
+	v4 := githubv4.NewClient(client.http)
+	err := v4.Mutate(context.Background(), &mutation, input, nil)
+
+	return err
+}
+
 func min(a, b int) int {
 	if a < b {
 		return a
diff --git a/command/pr.go b/command/pr.go
index ee529aa9f..83ddf7d13 100644
--- a/command/pr.go
+++ b/command/pr.go
@@ -29,6 +29,7 @@ func init() {
 	prMergeCmd.Flags().BoolP("merge", "m", true, "Merge the commits with the base branch")
 	prMergeCmd.Flags().BoolP("rebase", "r", false, "Rebase the commits onto the base branch")
 	prMergeCmd.Flags().BoolP("squash", "s", false, "Squash the commits into one commit and merge it into the base branch")
+	prCmd.AddCommand(prReadyCmd)
 
 	prCmd.AddCommand(prListCmd)
 	prListCmd.Flags().IntP("limit", "L", 30, "Maximum number of items to fetch")
@@ -84,13 +85,18 @@ var prReopenCmd = &cobra.Command{
 	Args:  cobra.ExactArgs(1),
 	RunE:  prReopen,
 }
-
 var prMergeCmd = &cobra.Command{
 	Use:   "merge [<number> | <url> | <branch>]",
 	Short: "Merge a pull request",
 	Args:  cobra.MaximumNArgs(1),
 	RunE:  prMerge,
 }
+var prReadyCmd = &cobra.Command{
+	Use:   "ready [<number> | <url> | <branch>]",
+	Short: "Make a pull request as ready for review",
+	Args:  cobra.MaximumNArgs(1),
+	RunE:  prReady,
+}
 
 func prStatus(cmd *cobra.Command, args []string) error {
 	ctx := contextForCommand(cmd)
@@ -551,6 +557,66 @@ func printPrPreview(out io.Writer, pr *api.PullRequest) error {
 	return nil
 }
 
+func prReady(cmd *cobra.Command, args []string) error {
+	ctx := contextForCommand(cmd)
+	apiClient, err := apiClientForContext(ctx)
+	if err != nil {
+		return err
+	}
+
+	baseRepo, err := determineBaseRepo(apiClient, cmd, ctx)
+	if err != nil {
+		return err
+	}
+
+	var pr *api.PullRequest
+	if len(args) > 0 {
+		var prNumber string
+		n, _ := prFromURL(args[0])
+		if n != "" {
+			prNumber = n
+		} else {
+			prNumber = args[0]
+		}
+
+		pr, err = prFromArg(apiClient, baseRepo, prNumber)
+		if err != nil {
+			return err
+		}
+	} else {
+		prNumber, branchWithOwner, err := prSelectorForCurrentBranch(ctx, baseRepo)
+		if err != nil {
+			return err
+		}
+
+		if prNumber != 0 {
+			pr, err = api.PullRequestByNumber(apiClient, baseRepo, prNumber)
+		} else {
+			pr, err = api.PullRequestForBranch(apiClient, baseRepo, "", branchWithOwner)
+		}
+		if err != nil {
+			return err
+		}
+	}
+
+	if pr.Closed {
+		err := fmt.Errorf("%s Pull request #%d is closed. Only draft pull requests can be marked as \"ready for review\"", utils.Red("!"), pr.Number)
+		return err
+	} else if !pr.IsDraft {
+		fmt.Fprintf(colorableErr(cmd), "%s Pull request #%d is already \"ready for review\"\n", utils.Yellow("!"), pr.Number)
+		return nil
+	}
+
+	err = api.PullRequestReady(apiClient, baseRepo, pr)
+	if err != nil {
+		return fmt.Errorf("API call failed: %w", err)
+	}
+
+	fmt.Fprintf(colorableErr(cmd), "%s Pull request #%d is marked as \"ready for review\"\n", utils.Green("✔"), pr.Number)
+
+	return nil
+}
+
 // Ref. https://developer.github.com/v4/enum/pullrequestreviewstate/
 const (
 	requestedReviewState        = "REQUESTED" // This is our own state for review request
diff --git a/command/pr_test.go b/command/pr_test.go
index 528e2ee77..24fce9d63 100644
--- a/command/pr_test.go
+++ b/command/pr_test.go
@@ -1093,3 +1093,72 @@ func TestPrMerge_alreadyMerged(t *testing.T) {
 		t.Fatalf("output did not match regexp /%s/\n> output\n%q\n", r, output.Stderr())
 	}
 }
+
+func TestPRReady(t *testing.T) {
+	initBlankContext("", "OWNER/REPO", "master")
+	http := initFakeHTTP()
+	http.StubRepoResponse("OWNER", "REPO")
+	http.StubResponse(200, bytes.NewBufferString(`
+	{ "data": { "repository": {
+		"pullRequest": { "number": 444, "closed": false, "isDraft": true}
+	} } }
+	`))
+	http.StubResponse(200, bytes.NewBufferString(`{"id": "THE-ID"}`))
+
+	output, err := RunCommand("pr ready 444")
+	if err != nil {
+		t.Fatalf("error running command `pr ready`: %v", err)
+	}
+
+	r := regexp.MustCompile(`Pull request #444 is marked as "ready for review"`)
+
+	if !r.MatchString(output.Stderr()) {
+		t.Fatalf("output did not match regexp /%s/\n> output\n%q\n", r, output.Stderr())
+	}
+}
+
+func TestPRReady_alreadyReady(t *testing.T) {
+	initBlankContext("", "OWNER/REPO", "master")
+	http := initFakeHTTP()
+	http.StubRepoResponse("OWNER", "REPO")
+	http.StubResponse(200, bytes.NewBufferString(`
+	{ "data": { "repository": {
+		"pullRequest": { "number": 445, "closed": false, "isDraft": false}
+	} } }
+	`))
+	http.StubResponse(200, bytes.NewBufferString(`{"id": "THE-ID"}`))
+
+	output, err := RunCommand("pr ready 445")
+	if err != nil {
+		t.Fatalf("error running command `pr ready`: %v", err)
+	}
+
+	r := regexp.MustCompile(`Pull request #445 is already "ready for review"`)
+
+	if !r.MatchString(output.Stderr()) {
+		t.Fatalf("output did not match regexp /%s/\n> output\n%q\n", r, output.Stderr())
+	}
+}
+
+func TestPRReady_closed(t *testing.T) {
+	initBlankContext("", "OWNER/REPO", "master")
+	http := initFakeHTTP()
+	http.StubRepoResponse("OWNER", "REPO")
+	http.StubResponse(200, bytes.NewBufferString(`
+	{ "data": { "repository": {
+		"pullRequest": { "number": 446, "closed": true, "isDraft": true}
+	} } }
+	`))
+	http.StubResponse(200, bytes.NewBufferString(`{"id": "THE-ID"}`))
+
+	_, err := RunCommand("pr ready 446")
+	if err == nil {
+		t.Fatalf("expected an error running command `pr ready` on a review that is closed!: %v", err)
+	}
+
+	r := regexp.MustCompile(`Pull request #446 is closed. Only draft pull requests can be marked as "ready for review"`)
+
+	if !r.MatchString(err.Error()) {
+		t.Fatalf("output did not match regexp /%s/\n> output\n%q\n", r, err.Error())
+	}
+}